AlturLab – Pioneering Mangiferin and Salidroside for Advanced Health Solutions

At AlturLab, we are dedicated to advancing the science of natural bioactive compounds through innovative extraction and biotechnological processes. Our expertise centers on two flagship molecules, mangiferin and salidroside, each with unique origins and remarkable health benefits.

 

Mangiferin: a versatile molecule that helps with many of the problems that appear with aging.

Mangiferin is a powerful natural polyphenol primarily sourced from the leaves of the mango tree (Mangifera indica).

This molecule is celebrated for its ability to:

increases reactivity in humans (i.e. increases reaction speed)

-Modulate inflammation, supporting joint and metabolic health.

-Promote neuroprotection,

- safeguarding cognitive function.

Support healthy glucose metabolism and cardiovascular function.

-Neutralize free radicals, offering robust antioxidant protection.

 

 

Salidroside: the main active ingredient in rhodiola is now produced  produced in bioreactors...and that changes a lot of things

Salidroside is a phenylpropanoid glycoside recognized for its adaptogenic, anti-fatigue, neuroprotective, and cardioprotective effects. Traditionally, it was extracted from the roots of Rhodiola rosea, but the increasing demand and the need to protect wild Rhodiola populations have led to a breakthrough in its production.

 

Today, salidroside is produced sustainably through microbial fermentation in bioreactors. This process, developed by leaders like Gnosis by Lesaffre, involves genetically engineered microorganisms that biosynthesize pure salidroside under controlled conditions. The result is a standardized, high-purity ingredient that is environmentally friendly and consistent in quality.

 

Clinical research on fermentation-derived salidroside has shown benefits such as:

 

Improved cardiovascular fitness and aerobic endurance

 

Reduced muscle damage and faster recovery after exercise

 

Enhanced mood stability during periods of intense physical activity

 

Next-Generation Delivery: Niosomes and Liposomes

To maximize the effectiveness of these bioactives, we are exploring advanced delivery systems. Liposomes, made from natural phospholipids, are already widely used for their excellent biocompatibility and ability to encapsulate both water- and fat-soluble molecules. They help protect sensitive ingredients and improve their absorption in the body.

 

Niosomes, on the other hand, are vesicles formed from non-ionic surfactants. They offer potential advantages in stability and cost compared to liposomes and can also encapsulate a wide variety of active compounds. However, developing niosome-based delivery systems presents significant challenges, including formulation stability and scalability. This makes niosomes a promising but complex area of research that we are committed to advancing.

 

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